Infertility and Genetics

Genetics of infertility. About 10–15% of human couples are infertile, unable to conceive. In approximately in half of these cases, the underlying cause is related to the male. Genetic factors including aneuploidies and single-gene mutations are also contributed to the male infertility. Infertility is common. Out of 100 couples in the United States, about 12 to 13 of them have trouble becoming pregnant. About one-third of infertility cases are caused by fertility problems in women, and another one-third of fertility problems are due to fertility problems in men.